Malignant Histiocytoma with Brain Metastasis

Malignant Fibrous Histiocytoma with In-Transit Metastasis

Malignant fibrous histiocytoma (MFH) is the most common fibroblastic tumor, but its cutaneous metastasis, especially in-transit metastasis, is extremely rare. We describe the case of a 30-year-old Japanese man with a recurrent MFH on the scalp accompanied by in-transit metastasis, which had been treated as a benign skin tumor 8 years before. The main bulk of the recurrent tumor was located in t...

Intraparenchymal Brain Malignant Fibrous Histiocytoma

A 60-year-old man, with a history of hypercholesterolemia and left leg deep vein thrombosis, was admitted to hospital following two weeks of headaches and expressive aphasia. Neurological examination confirmed expressive aphasia in the absence of motor, sensory or cranial nerve deficit. A total body computer tomography (CT) imaging showed a single intraparenchymal lesion with a central necrotic...

Cardiac metastasis in malignant fibrous histiocytoma.

Malignant fibrous histiocytoma MFH is an aggressive spindle cell cancer and is the most common soft tissue tumor in the elderly, primarily affecting the extremities. It has high metastatic potential and can spread to various viscera including liver, lung, bone, and brain; however, cardiac metastasis is an extreme rarity. Here, we present a 50-year-old male, diagnosed as pleiomorhphic storiform ...

Malignant fibrous histiocytoma.

Calvarial malignant fibrous histiocytoma.

Primary malignant fibrous histiocytoma (MFH) of the central nervous system (CNS) is uncommon. We report cases of two young patients of MFH arising from the cranial meninges and involving the adjacent skull and scalp. There was infiltration of the brain in one case. Both the lesions were excised and primary scalp repair was performed.